Specialist expertise
In-vivo Pharmacokinetic (PK) and Pharmacodynamic (PD)
Animal model testing (mice, rats) for dose-response, safety, efficacy, and lead optimization.
The science
About this capability
PK/ PD services evaluate how a drug moves through a living system (ADME: absorption, distribution, metabolism, excretion) and its biological effect, respectively. We utilize animal models (i.e., mice, rats) to determine dose-response, safety, efficacy, and lead compound optimization, typically utilizing techniques like ELISA and LC-MS/MS for analysis.
Technical scope
- Animal models (mice, rats) for PK/PD testing
- Dose-response, safety, and efficacy determination
- Blood-To-Plasma Partition Ratio Determination (erythrocyte binding)
- ELISA and LC-MS/MS bioanalytical quantification
Let’s work together
The right expertise.
For your next step.
Talk with our scientific team about your requirements,
technical feasibility, and timelines.
What happens next
- Share your requirementsTell us about your research goals, scope, and timelines.
- Scientific consultationOur scientists review feasibility and discuss the best approach with you.
- Proposal and quoteReceive a clear proposal covering scope, deliverables, timelines, and cost.