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Chemistry R&D

SFC Purification

Chiral separation and preparative purification to support your chemistry and drug discovery programs.

  • Chiral separation
  • Preparative SFC
  • HPLC

The science

Service overview

We offer chiral purification using preparative Supercritical Fluid Chromatography (Prep-SFC) and Preparative High Performance Liquid Chromatography (Prep-HPLC). Our expert scientists produce high-quality compounds from milligrams to hundreds of grams with a fast turnaround time.

How we can help

Our capabilities

Explore the services and methods available for your project.

Chiral Separation Method Development

Rapid screening of chiral stationary phases and co-solvent conditions on Analytical SFC systems to achieve baseline resolution.

Preparative SFC / HPLC Scale-Up

High-throughput isolation utilizing Preparative SFC and Prep-HPLC systems scaling from milligrams to kilograms.

Impurity Isolation & Library Purification

Isolation of impurities in starting materials, intermediates, APIs, and high-throughput purification of compound libraries.

Fraction Recovery & Purity QC

Rapid CO₂ removal, high-purity fraction recovery, and analytical QC to >98–99% ee/purity, with a Certificate of Analysis.

Explore in detail

Technical resources

Open a section to explore our full service scope and instrumentation.

Methods & service scope5 areas of expertise
  • Purification of chiral compounds.
  • Isolation of impurities in starting materials, intermediates, APIs and drug products.
  • Purification of either single compounds or libraries.
  • High-throughput purification for synthetic compounds.
  • Chiral separation method development.
Instrumentation & platforms3 instruments and capabilities
  • Preparative SFC System - Rapid, green, and high-efficiency purification for chiral and achiral compounds
  • Analytical SFC System - Rapid, high-resolution results for complex mixtures in pharmaceutical R&D
  • Preparative HPLC & High-Throughput Fraction Collectors

Let’s work together

The right expertise.
For your next step.

Talk with our scientific team about your requirements,
technical feasibility, and timelines.

What happens next

  1. Share your requirementsTell us about your research goals, scope, and timelines.
  2. Scientific consultationOur scientists review feasibility and discuss the best approach with you.
  3. Proposal and quoteReceive a clear proposal covering scope, deliverables, timelines, and cost.