Target Identification and Validation
Identifying biological targets involved in disease and validating their therapeutic potential.
Chemistry R&D
Medicinal Chemistry & Drug Design
Design, synthesize, and optimize drug candidates with chemistry support from target identification through preclinical development.
- Hit-to-lead
- Lead optimization
- Preclinical
The science
Service overview
The foundation of any medicinal chemistry program for creating innovative medicines begins with the selection of a disease-specific drug target. Drug targets can be molecular receptors, enzymes or transporters. Medicinal chemistry is integral to the drug discovery process, bridging the gap between chemical synthesis and biological efficacy. By focusing on the design, synthesis, and optimization of potential drugs, medicinal chemists play a crucial role in bringing new therapies to market.
How we can help
Our capabilities
Explore the services and methods available for your project.
Hit Identification
Using high-throughput screening (HTS) and libraries to find compounds (hits) that interact with the target.
Hit-to-Lead Phase
Optimizing initial hits by creating analogs to refine their interaction with the biological target.
Lead Optimization
Modifying lead compounds to improve potency, selectivity, and pharmacokinetics (absorption, distribution, metabolism, excretion—ADME).
Preclinical Development
Preparing candidate molecules for clinical trials, focusing on scaling up synthesis and evaluating toxicity.
Explore in detail
Technical resources
Open a section to explore our full service scope and instrumentation.
Methods & service scope2 areas of expertise
- CUSTOM SYNTHESIS
Synthesis of Active Pharmaceutical Ingredients (APIs), Pro-drugs, Peptides, Bio-conjugates, Key Chemical and Cosmetic Intermediates, Building blocks…
- MEDICINAL CHEMISTRY
Re-synthesis of hits, Hit-to-Lead & Lead optimization chemistry to achieve optimum Pharmaco-Kinetic (PK) properties with improved Bioavailability and Solubility Properties…
Instrumentation & platforms4 instruments and capabilities
- Structure-Activity Relationship (SAR): Systematically changing chemical structures to understand which features drive binding and effectiveness.
- Computer-Aided Drug Design (CADD): Utilizing molecular modeling and computational tools to design drugs (ligands) that fit into target binding sites.
- ADMET Optimization: Ensuring compounds have high absorption, distribution, metabolism, excretion, and low toxicity (ADMET).
- Synthetic Chemistry: Using organic synthesis to create novel chemical compounds in the lab.
Let’s work together
The right expertise.
For your next step.
Talk with our scientific team about your requirements,
technical feasibility, and timelines.
What happens next
- Share your requirementsTell us about your research goals, scope, and timelines.
- Scientific consultationOur scientists review feasibility and discuss the best approach with you.
- Proposal and quoteReceive a clear proposal covering scope, deliverables, timelines, and cost.