Enzymatic & Target Binding Profiling
Custom biochemical assays built around target biology providing robust, high-quality data.
Biology & Assays
Biochemical & Biophysical Assays
Characterize target activity, binding, and engagement with biochemical and biophysical assays built around your research target.
- Enzyme kinetics
- SPR
- Thermal shift
The science
Service overview
We provide custom biochemical assays built around your target biology, together with biophysical assays for binding, kinetics, and target engagement. Combining advanced technologies with deep expertise, we deliver robust, high-quality data to guide hit identification and mechanism-of-action studies.
How we can help
Our capabilities
Explore the services and methods available for your project.
Label-Free Binding Kinetics & Engagement
High-throughput biophysical solutions for binding, kinetics, and target engagement.
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Technical resources
Open a section to explore our full service scope and instrumentation.
Methods & service scope6 areas of expertise
- Enzyme Kinetics & Inhibition
Determining Ki, IC50, and mechanism of action across target enzyme classes.
- Recombinant Target Screening
Assaying kinases, phosphatases, proteases, GPCRs, and epigenetic enzymes.
- Protein-Protein Interaction (PPI)
Quantifying complex formation and identifying small molecule disruptors.
- Surface Plasmon Resonance (SPR)
Real-time, label-free binding affinity (Kd) and kinetic rate constants (ka, kd).
- Target Engagement & Thermal Shift
Thermal Shift Assays (DSF/nanoDSF) evaluating ligand-induced protein stabilization.
- Direct Physical Binding Profiling
Validating direct physical binding of small molecules, peptides, and fragments.
Instrumentation & platforms3 instruments and capabilities
- Molecular Biology
- Surface Plasmon Resonance (SPR) & Biophysical Analyzers
- Bioinformatics and Computational Biology for Drug Discovery
Let’s work together
The right expertise.
For your next step.
Talk with our scientific team about your requirements,
technical feasibility, and timelines.
What happens next
- Share your requirementsTell us about your research goals, scope, and timelines.
- Scientific consultationOur scientists review feasibility and discuss the best approach with you.
- Proposal and quoteReceive a clear proposal covering scope, deliverables, timelines, and cost.