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Analytical & DMPK

Bioanalysis

Bioanalytical methods, biomarker analysis, and immunogenicity testing to support discovery and preclinical research.

  • LC-MS/MS
  • PK/PD
  • Biomarkers
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The science

Service overview

Our bioanalytical team provides comprehensive bioanalytical services, including assay and method development, molecular biology, LC-MS, ligand binding assays (LBA), immunogenicity testing, biomarker analysis, flow cytometry, and more, supporting your program from discovery through preclinical development.

How we can help

Our capabilities

Explore the services and methods available for your project.

Biomarkers

Biomarker Testing: A Key Tool to accelerate drug development by identifying and validating molecular indicators of disease and treatment response.

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Immunogenicity

Bioanalytical support for immunogenicity testing of therapeutics to detect, characterize, and quantify anti-drug antibodies (ADAs) and neutralizing antibodies (NAbs).

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How a project runs

Research workflow

4 stages, with a clear outcome at each step.

  1. Assay Development & Validation

    Designing and validating specific, precise assays (ELISA, MSD, LBA, cell-based) and 'fit-for-purpose' biomarker panels.

    Outcome: Fit-For-Purpose Assays

  2. Sample Analysis & Bioanalysis

    Executing high-sensitivity bioanalysis across biological samples (blood, tissue, fluid) using LC-MS/MS, qPCR, and flow cytometry.

    Outcome: GLP Sample Testing

  3. PK/PD & Immunogenicity Evaluation

    Integrating PK/PD data to establish dose-response relationships and conducting tiered immunogenicity screening (ADAs/NAbs).

    Outcome: PK/PD & ADA Profiling

  4. Diagnostic & Translational Reporting

    Delivering decision-ready diagnostic reports (LDTs, immunology, infectious disease) and regulatory-compliant documentation.

    Outcome: Decision-Ready Reports

Inside our laboratory

The instruments behind your results

Full instrument list

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Technical resources

Open a section to explore our full service scope and instrumentation.

Methods & service scope5 areas of expertise
  • In-Vivo Pharmacokinetics & Pharmacodynamics (LC/MS, HPLC, Flow Cytometry, qPCR)
  • Assay Development & Validation (ELISA, MSD, SPR for biomarkers & genetic markers)
  • Biomarker Testing & Quantification (multiomics, MSD-ECL, Luminex multiplexing)
  • Immunogenicity Testing (anti-drug antibodies ADAs & neutralizing antibodies NAbs)
  • Specialized Diagnostic Testing (vitamins/supplements, LDTs, diagnostic immunology)
Instrumentation & platforms5 instruments and capabilities
  • Mass Spectrometry (MS) Platforms (i.e., LC-MS/MS, ICP-MS)
  • Specialized Analytical Techniques (i.e., NMR, TEM)
  • Immunoassay and Ligand Binding Assay (LBA) Platforms (i.e., ELISA, ECD/MSD)
  • Molecular Biology and Cellular Analysis (i.e., qPCR, Flow Cytometry and Cell-based assays)
  • Advanced Sample Preparation and Handling (i.e., Automated Liquid Handling, Micro-sampling Techniques like DBS or DPS)

Let’s work together

The right expertise.
For your next step.

Talk with our scientific team about your requirements,
technical feasibility, and timelines.

Discuss your project
+1 604-339-3244

What happens next

  1. Share your requirementsTell us about your research goals, scope, and timelines.
  2. Scientific consultationOur scientists review feasibility and discuss the best approach with you.
  3. Proposal and quoteReceive a clear proposal covering scope, deliverables, timelines, and cost.