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Specialist expertise

Strategic Consultation & Discovery Planning

Turning therapeutic targets into viable clinical candidates.

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The science

About this capability

Strategic consultation and discovery planning for antibody drug discovery involve a structured, multi-disciplinary approach to turn a therapeutic target into a viable clinical candidate. This process includes target validation, generation of diverse antibody pools, and optimization of druggability to ensure successful development.

Technical scope

  • Clients’ Needs Assessment: Collaborate to understand their therapeutic goals.
  • Customized Roadmap: Create a customized plan, from target discovery to preclinical validation, aligned with their objectives.

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Target Identification & Therapeutic Candidate Screening

Identifying disease-associated molecules (proteins, receptors) and selecting high-affinity antibodies through in-vivo/in-vitro screening.

Chemistry: Lead Optimization & ADC Design

Iterative phases combining antibody engineering, linker chemistry, and cytotoxic payload selection to refine ADC structure for efficacy and safety.

Proof of Concept (POC) Studies

Early-stage preclinical assessments validating candidate antibody binding affinity, target specificity, functional efficacy, and stability.

In-Vitro & In-Vivo Validation

Transitioning candidates from initial binding screens to functional development via in-vitro bioassays and in-vivo tumor xenograft studies.

Preclinical Development

Optimizing lead antibodies through affinity maturation, humanization, and Fc engineering, and scaling up conjugation processes.

Regulatory Support & IND Application

Ensuring compliance with FDA guidelines from target validation to IND submission, including QTPP, mAb characterization, and CMC compliance.

Let’s work together

The right expertise.
For your next step.

Talk with our scientific team about your requirements,
technical feasibility, and timelines.

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+1 604-339-3244

What happens next

  1. Share your requirementsTell us about your research goals, scope, and timelines.
  2. Scientific consultationOur scientists review feasibility and discuss the best approach with you.
  3. Proposal and quoteReceive a clear proposal covering scope, deliverables, timelines, and cost.