Chemical Building Blocks
Pharma Inventors Inc., offer chemical building blocks that are new & those known in the literature but not readily available. These building blocks will have orthogonal chemical functionalities for analogue generation for screening against a drug receptor of interest. Some of these building blocks have drug like core structures and are specially designed based on the most recent understandings in medicinal chemistry to facilitate optimization of ADME properties.
As you know, pre-clinical drug discovery is a complex process and it is often faced with many challenges for the optimization of physico-chemical and pharmacokinetic properties of new drug molecules. Such properties include intrinsic clearance (CLint), rate and extent of solubility in physiological fluids (pH 5.5-7.5), protein-binding and so on. Switching to more rigid and yet hydrophilic core structures (our building blocks) can potentially solve some of these challenges.
Please Contact Us for a detailed list of chemical building blocks and their competitive pricing.
Screening Compounds
Scientists at Pharma Inventors Inc., have more than 15 years of hands-on experience with diverse chemical compounds. Our screening libraries are suitable for high throughput screening or you can choose a select set of compounds for screening against the drug target of your choice. We offer defined quantities of the customized library of compounds to help you succeed in finding lead-like structures for the target of your choice.
These structures are designed to minimize false-positive results and have reduced toxico-kinetic & drug-like properties. We also offer consultation services to guide you through the compound selection process.
Below is general shipment information for the library of compounds :
Laboratory Chemicals & Reagents
Pharma Inventors Inc. offers laboratory chemicals and reagents that you find in catalogues but have quantity restrictions or require long wait times. Our scientists are here to help you get going with your research projects without compromising on your research ideas and not miss deadlines.